The two major categories for vulvar lesions are tumors of epithelial origin and tumors of mesenchymal origin. The tumor is firm with rolled borders, and most often is found on the labia majora of postmenopausal women. Carcinoma in situ showing hyperkeratotic pigmented epithelial thickening. Some may have an origin in the eccrine sweat glands. There is hyperplasia in the epidermis, and increased melanin in the basal layer of skin. Management is incision and drainage, with or without marsupialization.
The histologic appearance is similar to that of leiomyomas Fig.
Vulvar vascular tumors: a clinicopathologic study of 85 patients.
Case Reports in Obstetrics and Gynecology. The affected areas may be asymptomatic or excoriated from scratching. Grossly, they present as multiple, white or gray, vascular nodules with epithelial thickening. HPV infections are classified as either clinical or subclinical, contingent on the infectivity of the virus and the response of the affected epithelium. Lentigines are small 1 to 4 mmwell-circumscribed macules. Mitotic figures are frequent. The tumor infiltrates the underlying tissue and may ulcerate if it reaches the epidermis.